Male genital lichen sclerosus and filaggrin
نویسندگان
چکیده
منابع مشابه
Review of the male genital lichen sclerosus and urethral involvement
Lichen sclerosus (LS) previously known as balanitis xerotica obliterans, is a chronic, progressive lymphocyte mediated skin disease. It shows a predilection for the male genital area and may involve in external urinary meatus, penile urethra and even bulbar urethra causing stricture. Male genital lichen sclerosus (MGLSc) may lead to a significant impairment of urinary and sexual function; and i...
متن کاملTopical interventions for genital lichen sclerosus.
BACKGROUND Lichen sclerosus is a chronic, inflammatory skin condition that most commonly occurs in adult women, although it may also be seen in men and children. It primarily affects the genital area and around the anus, where it causes persistent itching and soreness. Scarring after inflammation may lead to severe damage by fusion of the vulval lips (labia); narrowing of the vaginal opening; a...
متن کاملPolydeoxyribonucleotide Dermal Infiltration in Male Genital Lichen Sclerosus: Adjuvant Effects during Topical Therapy
Background. Lichen sclerosus (LS) is an autoimmune inflammatory skin disease that leads to tissue sclerosis. Actually, the first-line treatment consists of local steroid as clobetasol propionate (CP). Polydeoxyribonucleotide (PDRN) has demonstrated anti-inflammatory effects through the reduction of cytokine production and growth stimulation of fibroblast. Objective. To evaluate the efficacy of ...
متن کاملHistological evidence of urethral involvement in male patients with genital lichen sclerosus: a preliminary report.
PURPOSE Using pathological examination we evaluated the involvement of lichen sclerosus in urethral strictures in men. MATERIALS AND METHODS We performed an observational, descriptive, retrospective study of patients treated for genital lichen sclerosus who had at least 1 biopsy positive for lichen sclerosus. Study exclusion criteria were malignant penile lesions, incomplete data on personal ...
متن کاملUltrapotent topical corticosteroid treatment of childhood genital lichen sclerosus.
OBJECTIVE To observe the clinical effects of short-term application of ultrapotent topical corticosteroid on symptomatic genital lesions of lichen sclerosus in pediatric patients. DESIGN Case series of 10 prepubertal girls with genital lichen sclerosus. Ultrapotent topical corticosteroids were applied twice daily for 6 to 8 weeks and patients were reexamined at completion of treatment. Long-t...
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ژورنال
عنوان ژورنال: Clinical and Experimental Dermatology
سال: 2019
ISSN: 0307-6938,1365-2230
DOI: 10.1111/ced.14023